Title |
Haplotype-assisted accurate non-invasive fetal whole genome recovery through maternal plasma sequencing
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Published in |
Genome Medicine, February 2013
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DOI | 10.1186/gm422 |
Pubmed ID | |
Authors |
Shengpei Chen, Huijuan Ge, Xuebin Wang, Xiaoyu Pan, Xiaotian Yao, Xuchao Li, Chunlei Zhang, Fang Chen, Fuman Jiang, Peipei Li, Hui Jiang, Hancheng Zheng, Lei Zhang, Lijian Zhao, Wei Wang, Songgang Li, Jun Wang, Jian Wang, Huanming Yang, Yingrui Li, Xiuqing Zhang |
Abstract |
The applications of massively parallel sequencing technology to fetal cell-free DNA (cff-DNA) have brought new insight to non-invasive prenatal diagnosis. However, most previous research based on maternal plasma sequencing has been restricted to fetal aneuploidies. To detect specific parentally inherited mutations, invasive approaches to obtain fetal DNA are the current standard in the clinic because of the experimental complexity and resource consumption of previously reported non-invasive approaches. |
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United Kingdom | 2 | 17% |
Spain | 1 | 8% |
China | 1 | 8% |
Montenegro | 1 | 8% |
Germany | 1 | 8% |
Unknown | 3 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 50% |
Scientists | 5 | 42% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
Geographical breakdown
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Netherlands | 1 | 2% |
Ireland | 1 | 2% |
Italy | 1 | 2% |
Belgium | 1 | 2% |
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United States | 1 | 2% |
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Researcher | 18 | 32% |
Student > Ph. D. Student | 11 | 19% |
Student > Master | 9 | 16% |
Other | 6 | 11% |
Student > Doctoral Student | 3 | 5% |
Other | 6 | 11% |
Unknown | 4 | 7% |
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Mathematics | 1 | 2% |
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Unknown | 5 | 9% |