| Title |
Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control
|
|---|---|
| Published in |
Nature Neuroscience, August 2016
|
| DOI | 10.1038/nn.4376 |
| Pubmed ID | |
| Authors |
Alessandro Furlan, Gioele La Manno, Moritz Lübke, Martin Häring, Hind Abdo, Hannah Hochgerner, Jussi Kupari, Dmitry Usoskin, Matti S Airaksinen, Guillermo Oliver, Sten Linnarsson, Patrik Ernfors |
| Abstract |
Despite the variety of physiological and target-related functions, little is known regarding the cellular complexity in the sympathetic ganglion. We explored the heterogeneity of mouse stellate and thoracic ganglia and found an unexpected variety of cell types. We identified specialized populations of nipple- and pilo-erector muscle neurons. These neurons extended axonal projections and were born among other neurons during embryogenesis, but remained unspecialized until target organogenesis occurred postnatally. Target innervation and cell-type specification was coordinated by an intricate acquisition of unique combinations of growth factor receptors and the initiation of expression of concomitant ligands by the nascent erector muscles. Overall, our results provide compelling evidence for a highly sophisticated organization of the sympathetic nervous system into discrete outflow channels that project to well-defined target tissues and offer mechanistic insight into how diversity and connectivity are established during development. |
X Demographics
The data shown below were collected from the profiles of 46 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 24% |
| United Kingdom | 6 | 13% |
| Canada | 2 | 4% |
| Italy | 2 | 4% |
| Germany | 2 | 4% |
| Australia | 2 | 4% |
| Norway | 1 | 2% |
| Ecuador | 1 | 2% |
| Brazil | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 15 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 30 | 65% |
| Scientists | 13 | 28% |
| Science communicators (journalists, bloggers, editors) | 2 | 4% |
| Practitioners (doctors, other healthcare professionals) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Sweden | 2 | 1% |
| Finland | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 152 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 38 | 24% |
| Researcher | 32 | 20% |
| Student > Bachelor | 13 | 8% |
| Student > Doctoral Student | 10 | 6% |
| Other | 6 | 4% |
| Other | 24 | 15% |
| Unknown | 35 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 38 | 24% |
| Agricultural and Biological Sciences | 32 | 20% |
| Biochemistry, Genetics and Molecular Biology | 25 | 16% |
| Medicine and Dentistry | 14 | 9% |
| Psychology | 4 | 3% |
| Other | 9 | 6% |
| Unknown | 36 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 241. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2024.
All research outputs
#156,688
of 25,477,125 outputs
Outputs from Nature Neuroscience
#245
of 5,632 outputs
Outputs of similar age
#3,154
of 349,296 outputs
Outputs of similar age from Nature Neuroscience
#8
of 79 outputs
Altmetric has tracked 25,477,125 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,632 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 57.5. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.