@YellowJ97022132 @PlusDeSauvage @Arwed1211 @Catcat97553138 @CuveLe @MartinZ_uncut https://t.co/7qBi1AEgF1 l'ironie c'est donc que ce type de molécule agoniste de voie STING sont utilisé en immuno oncologie, j'ai même participé a la preuve de concept d'une
RT @CommsBio: Su Chul Jang et al engineered an extracellular vesicle loaded with a potent cyclic dinucleotide agoist of the STING pathway.…
以前紹介したけど, 腫瘍内特異的にSTINGを活性化してType I IFNで自然免疫を活性化する作戦も https://t.co/YsCfenTE43
Su Chul Jang et al engineered an extracellular vesicle loaded with a potent cyclic dinucleotide agoist of the STING pathway. ExoSTING was retained better in tumors and produced lower levels of systemic inflammatory cytokine production. @codiakbio https://
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance | Communications Biology https://t.co/FQUz7NKc7O
up 34% on publication. "ExoSTING (0.2 µg) injection showed robust inhibition of growth not only in the injected primary tumor but also in the non-injected contralateral tumors" https://t.co/A9x8bCMpYT https://t.co/PeOWpuVLbg
がん免疫を賦活化するナノ粒子薬の開発! 腫瘍微小環境中の免疫細胞に対して特異的に自然免疫応答を活性化させる”ExoSTING”が開発された. 人工の細胞外小胞にSTINGのアゴニストとして環状ジヌクレオチドを封入した代物. 腫瘍外では炎症を惹起しない設計でなんと素晴らしい! https://t.co/YsCfenTE43
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance https://t.co/4Ehr4thsDF
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance https://t.co/iJJ0ax6E95