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#CRISPR/Cas9 を介した CNS 細胞型遺伝子の破壊を使用した、マウスにおける新生児の脳室内送達による #AAV の形質導入のプロファイリング https://t.co/jyj1ZN1Q9D AAV-CRISPR/sgNeuN の新生児 ICV 注射後、CNS 領域全体にて様々な #NeuN タンパク質減少を #PeggySue 検出 #ACD #RNAScope https://t.co/B4SIoi5Xuu
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Traditional methods of measuring transduction efficiency and tropism of adeno-associated virus (AAV) may underestimate AAV transduction. Torregrosa et al., looked to CRISPR/Cas9 as an alternative means to measure transduction. Read the full paper here: htt
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Traditional methods of measuring transduction efficiency and tropism of adeno-associated virus (AAV) may underestimate AAV transduction. Torregrosa et al., looked to CRISPR/Cas9 as an alternative means to measure transduction. Read the full paper here: htt
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Use of #CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice. Torregrosa T et al. Gene Ther 2021-02-22. https://t.co/bFh8ORsSPd Intraventricular injection: AAV9, AAV-PHP
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Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice https://t.co/N7qp9IpaH9 https://t.co/nJfkR60amM
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RT @saintlukman: Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventr…
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Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice https://t.co/PR3wEiDvJY https://t.co/7VK34OcW3z